Sulforaphane and human health
Over the past 25 years, the cancer protective effects of broccoli and other cruciferous vegetables have been well documented by a substantive body of scientific literature. The glucosinolates, which are found almost exclusively in cruciferous vegetables, are believed to largely convey this therapeutic benefit via the release of bioactive isothiocyanates, such as sulforaphane.
The mechanistic basis behind the observed cancer protective effect of sulforaphane appears to involve the modulation of multiple pathways: tumour initiation, promotion and progression phases, and also by suppressing the final steps of carcinogenesis.
Leadership in the clinical development of sulforaphane
Despite its clinical promise, the development of sulforaphane as a human therapeutic has hitherto not been viable due its inherent instability. However, in a significant technical breakthrough, the molecule has been successfully stabilised and its clinical potential can now be fully investigated for the first time.
By using a portfolio of patented technologies, Evgen has uniquely positioned itself to take leadership in the clinical development of sulforaphane for the prevention and treatment of a number of human diseases.