Glucosinolates, isothiocyanates and human health
The cancer protective effects of broccoli and other cruciferous vegetables have been well documented in the epidemiologic literature over the past 25 years. The glucosinolates, which are found almost exclusively in cruciferous vegetables, are largely believed to convey these therapeutic benefits via the release of bioactive isothiocyanates †.
In addition to the prevention and treatment of some cancers, these molecules have also demonstrated clinical potential in the treatment of age-related macular degeneration, hypertension, asthma and the elimination of H. pylori; the causative agent of ulcers and gastritis, and is a major risk factor for the development of gastric cancer.
Leadership in commercialisation of pure glucosinolate compounds
To date, the commercialisation of pure glucosinolates has been impractical due to the economics and complexity of chemical synthesis or extraction from botanical sources. By using industrial biotechnology, protected by a strong intellectual property position, Evgen intends to take leadership in the clinical development and commercialisation of pure glucosinolates and the controlled delivery of their active metabolites for the prevention and treatment of human disease.
† Traka M., Mithen R. F. (2009) Glucosinolates, isothiocyanates and human health Phytochemistry Reviews 8 (1) 269-282